Perfluorophenyl acetate
pentafluorophenyl acetate
CAS: 19220-93-0
Molecular Formula: C8H3F5O2
Perfluorophenyl acetate - Names and Identifiers
| Name | pentafluorophenyl acetate |
| Synonyms | NSC 168737 Perfluorophenyl acetate perfluorophenyl acetate Pentafluorophenyl Acete PENTAFLUOROPHENYL ACETATE pentafluorophenyl acetate acetic acid pentafluorophenyl ester Phenol,2,3,4,5,6-pentafluoro-, 1-acetate Acetic acid 2,3,4,5,6-pentafluorophenyl ester |
| CAS | 19220-93-0 |
| EINECS | 242-891-0 |
| InChI | InChI=1/C8H3F5O2/c1-2(14)15-8-6(12)4(10)3(9)5(11)7(8)13/h1H3 |
Perfluorophenyl acetate - Physico-chemical Properties
| Molecular Formula | C8H3F5O2 |
| Molar Mass | 226.1 |
| Density | 1.526±0.06 g/cm3(Predicted) |
| Melting Point | 27-30°C |
| Boling Point | 59-60°C12mm Hg |
| Flash Point | 70.8°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.63mmHg at 25°C |
| Appearance | powder to lump |
| Color | White to Almost white |
| BRN | 1985849 |
| Storage Condition | Inert atmosphere,2-8°C |
| Refractive Index | 1.421 |
Perfluorophenyl acetate - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
Perfluorophenyl acetate - Introduction
pentafluorophenyl acetate is a practical pentafluorophenyl ester protected by an organic compound. The following is a description of the nature, use, preparation and safety information of pentafluorophenyl acetate:
Nature:
pentafluorophenyl acetate is a colorless to pale yellow liquid with a strong aromatic odor. It is insoluble in water, but soluble in organic solvents.
Use:
pentafluorophenyl acetate is widely used in organic synthesis reactions. It is often used as a protective group for the pentafluorophenyl group to prevent the occurrence of accidental functional groups in other reactions. In addition, pentafluophenyl acetate is also commonly used in the preparation of compounds in the fields of medicine, pesticides and materials science.
Method:
pentafluorophenyl acetate is generally prepared by reacting pentafluorophenol and acetic anhydride under acidic conditions. The reaction is generally carried out under an inert atmosphere in order to avoid possible explosion hazards.
Safety Information:
pentafluorophenyl acetate is an organic compound, which should be used safely. It is irritating and toxic and may cause damage to the skin and eyes. Appropriate personal protective equipment such as goggles, gloves and lab coats should be worn during operation. Avoid inhalation, ingestion or contact with this substance and avoid mixing with other chemicals. Observe proper safe practices during storage and handling and comply with regulations regarding the use and handling of the substance.
Please carefully read and follow the relevant safety information and operating instructions before using pentafluorophenyl acetate in the laboratory.
Nature:
pentafluorophenyl acetate is a colorless to pale yellow liquid with a strong aromatic odor. It is insoluble in water, but soluble in organic solvents.
Use:
pentafluorophenyl acetate is widely used in organic synthesis reactions. It is often used as a protective group for the pentafluorophenyl group to prevent the occurrence of accidental functional groups in other reactions. In addition, pentafluophenyl acetate is also commonly used in the preparation of compounds in the fields of medicine, pesticides and materials science.
Method:
pentafluorophenyl acetate is generally prepared by reacting pentafluorophenol and acetic anhydride under acidic conditions. The reaction is generally carried out under an inert atmosphere in order to avoid possible explosion hazards.
Safety Information:
pentafluorophenyl acetate is an organic compound, which should be used safely. It is irritating and toxic and may cause damage to the skin and eyes. Appropriate personal protective equipment such as goggles, gloves and lab coats should be worn during operation. Avoid inhalation, ingestion or contact with this substance and avoid mixing with other chemicals. Observe proper safe practices during storage and handling and comply with regulations regarding the use and handling of the substance.
Please carefully read and follow the relevant safety information and operating instructions before using pentafluorophenyl acetate in the laboratory.
Last Update：2024-04-09 02:00:43
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